Arsenal’s record signing Pierre-Emerick Aubameyang starts on his debut against Everton at the Emirates Stadium.
The £55m striker lines up alongside fellow newcomer Henrikh Mkhitaryan, and Mesut Ozil who has just signed a new contract with the club. Alexandre Lacazette misses out and is among the substitutes.
Arsenal line up with a back four, while in midfield Aaron Ramsey is preferred to Jack Wilshere.
Everton hand a debut to loan signing Eliaquim Mangala, but Seamus Coleman is rested after playing a full match in midweek.
Wayne Rooney, Cenk Tosun and Gylfi Sigurdsson are among the subs.
ARSENAL: Cech, Bellerin, Mustafi, Koscielny, Monreal, Xhaka, Ramsey, Iwobi, Mkhitaryan, Ozil, Aubameyang… Subs: Ospina, Chambers, Kolasinac, Maitland-Niles, Elneny, Wilshere, Lacazette.
EVERTON: Pickford, Kenny, Keane, Williams, Mangala, Martina, Schneiderlin, Gueye, Walcott, Bolasie, Niasse… Subs: Joel, Rooney, Tosun, Sigurdsson, Davies, Calvert-Lewin, Holgate.